Folic Acid Awareness: The Essential Role of Methyl Folate in PCOS and Fertility

Folic Acid Awareness: The Essential Role of Methyl Folate in PCOS and Fertility

Jan 08, 2025Vicki Fletcher

During World Folic Acid Awareness Week, led by the International Federation for Spina Bifida and Hydrocephalus, we’re shining a spotlight on our supplement: Myo and D-Chiro Inositol with Methyl Folate.

This powerful blend is designed to support women experiencing hormonal imbalances, especially those managing PCOS. It does more than alleviate symptoms—it promotes fertility, emotional well-being, and metabolic health. The inclusion of Calcium L-Folate, the active form of folic acid, is a game-changer, helping prevent high blood sugar levels during pregnancy and significantly reducing the risk of neural tube defects. 

But before exploring the benefits of this supplement, let’s address an important distinction: folate vs. folic acid 

Folate vs. Folic Acid: What's the Difference? 

The terms folate and folic acid are often used interchangeably, but they are not the same. Both are forms of Vitamin B9, a key nutrient for cell growth, DNA synthesis, and red blood cell production. However, their forms and how they’re absorbed by the body differ: 

  • Folate is the natural form of Vitamin B9 found in foods such as leafy greens, legumes, and avocados. It is bioavailable, meaning the body can immediately use it. 

  • Folic Acid is the synthetic form found in supplements and fortified foods. It requires conversion in the liver to become active. However, some individuals have genetic variations that make this process inefficient, potentially leading to unmet nutritional needs. 

 What Is Methyl Folate? 

Methyl Folate (L-5-Methyltetrahydrofolate or L-5-MTHF), also known as levomefolic acid, is the active, bioavailable form of folate. Unlike folic acid, methyl folate does not require enzymatic conversion, making it immediately usable by the body. 

Key Features of Methyl Folate:

1. Active Form of Folate: 

Methyl folate is already in its active state, making it easier to absorb and utilize compared to synthetic folic acid.

2. Bypasses MTHFR Genetic Variations: 

Some individuals have a mutation in the MTHFR enzyme, impairing their ability to convert folic acid into its active form. Methyl folate bypasses this process, ensuring optimal absorption. 

3. Critical Roles in the Body:

  • DNA synthesis and repair: Essential for healthy cell growth.

  • Methylation processes: Regulates gene expression, detoxification, and neurotransmitter production. 

  • Homocysteine regulation: Converts homocysteine into methionine, supporting cardiovascular health. 

What Makes Our Myo and D-Chiro Inositol with Methyl Folate Special? 

1. Maximum Strength Formula for PCOS Support 

This supplement combines Myo-Inositol and D-Chiro Inositol in a clinically backed ratio to mimic the body’s natural balance. These nutrients work synergistically to: 

  • Regulate hormone levels 

  • Improve ovarian function 

  • Support metabolic health by promoting normal insulin function 

2. Added Folate for Preconception Health 

Folate is vital for women of childbearing age, especially those with PCOS, as it: 

  • Reduces the risk of neural tube defects during pregnancy 

  • Helps control blood sugar levels, benefiting women with insulin resistance 

3. Backed by Research 

Studies show that Myo-Inositol and D-Chiro Inositol significantly improve pregnancy rates in women with PCOS. 

4. Holistic Benefits Beyond Fertility 

This supplement supports overall well-being, including: 

  • Mood Stability: Boosts serotonin levels, helping reduce anxiety and depression. 

  • Blood Sugar Control: Promotes normal insulin function, reducing spikes and crashes. 

5. Easy-to-Take, High-Value Solution 

Each bottle contains 120 capsules, providing a 30-day supply. The fast-absorbing capsules are gentle on the stomach and easy to integrate into your daily routine. 

Why International Folic Acid Awareness Week Matters  

The International Federation for Spina Bifida and Hydrocephalus’ Folic Acid Awareness Week raises awareness about preventing neural tube defects, such as spina bifida, through proper supplementation and diet. We are helping amplify the key messages:   

  • Folic acid is essential for proper neural tube closure in the first 28 days after conception. 

  • It is nearly impossible to get sufficient folate from food alone. Supplements or fortified foods are necessary. 

  • Neural tube defects affect 1 in 500 newborns on average. 

  • The World Health Organization recommends taking 400 mcg of folic acid daily for at least 12 weeks before conception. 

Our supplements, Myo and D-Chiro Inositol with Methyl Folate are designed to support women’s hormones and reduce symptoms of PCOS.  The addition of folate can help prevent high blood sugar levels during pregnancy and has can prevent neural tube defects (NTD). It is also proved that Myo and D-Chiro Inositol with Methyl Folate can improve the rate of pregnancy in women living with PCOS. 

Directions for Use 

Take 4 capsules daily with water, preferably with a meal. Always consult your healthcare practitioner before starting any new supplement. 

Ingredients 

  • Capsule Shell (Hydroxypropylmethylcellulose) 

  • Inositol (Myo-Inositol) 

  • Bulking Agent (Microcrystalline Cellulose) 

  • D-Chiro Inositol 

  • Anti-Caking Agents (Magnesium Stearate, Silicon Dioxide) 

  • Calcium-L-Methylfolate (Folic Acid) 

 

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